2wpu

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==CHAPERONED RUTHENIUM METALLODRUGS THAT RECOGNIZE TELOMERIC DNA==
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<StructureSection load='2wpu' size='340' side='right' caption='[[2wpu]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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==Chaperoned ruthenium metallodrugs that recognize telomeric DNA==
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<StructureSection load='2wpu' size='340' side='right'caption='[[2wpu]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KYT:(3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III)'>KYT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1swh|1swh]], [[2bc3|2bc3]], [[1vwq|1vwq]], [[1sre|1sre]], [[1swf|1swf]], [[2rtb|2rtb]], [[1lcw|1lcw]], [[1hxz|1hxz]], [[1swp|1swp]], [[1rxj|1rxj]], [[1swe|1swe]], [[1mm9|1mm9]], [[2rto|2rto]], [[1swa|1swa]], [[2rtr|2rtr]], [[2rtd|2rtd]], [[1stp|1stp]], [[1n43|1n43]], [[2izh|2izh]], [[1sri|1sri]], [[1slf|1slf]], [[1swc|1swc]], [[1vwr|1vwr]], [[1swl|1swl]], [[1ndj|1ndj]], [[1str|1str]], [[1slg|1slg]], [[1vwm|1vwm]], [[1swd|1swd]], [[1swq|1swq]], [[1swu|1swu]], [[1i9h|1i9h]], [[1swj|1swj]], [[2rtj|2rtj]], [[2rtl|2rtl]], [[2iza|2iza]], [[1vwn|1vwn]], [[1vwk|1vwk]], [[1vwg|1vwg]], [[1moy|1moy]], [[1sts|1sts]], [[1hqq|1hqq]], [[1vwi|1vwi]], [[2izg|2izg]], [[1swg|1swg]], [[2izb|2izb]], [[1swk|1swk]], [[2izk|2izk]], [[1luq|1luq]], [[1sws|1sws]], [[1n4j|1n4j]], [[2izd|2izd]], [[1lcv|1lcv]], [[1swt|1swt]], [[1df8|1df8]], [[1vwl|1vwl]], [[1vwb|1vwb]], [[2rtk|2rtk]], [[1srj|1srj]], [[1kl3|1kl3]], [[2rti|2rti]], [[2izf|2izf]], [[1swr|1swr]], [[2rth|2rth]], [[2rtm|2rtm]], [[2izi|2izi]], [[1vwf|1vwf]], [[1vwh|1vwh]], [[1pts|1pts]], [[1mk5|1mk5]], [[1hxl|1hxl]], [[2f01|2f01]], [[1vwd|1vwd]], [[1nc9|1nc9]], [[1sle|1sle]], [[1vwj|1vwj]], [[2ize|2ize]], [[2rtf|2rtf]], [[2rtp|2rtp]], [[1n9y|1n9y]], [[1n9m|1n9m]], [[1hy2|1hy2]], [[1lcz|1lcz]], [[1nqm|1nqm]], [[1vwa|1vwa]], [[2izl|2izl]], [[1kl5|1kl5]], [[2izc|2izc]], [[1mep|1mep]], [[1sld|1sld]], [[1rxh|1rxh]], [[1rsu|1rsu]], [[1vwc|1vwc]], [[1nbx|1nbx]], [[1srh|1srh]], [[2izj|2izj]], [[1rst|1rst]], [[1kff|1kff]], [[1srg|1srg]], [[1vwe|1vwe]], [[2rtg|2rtg]], [[1rxk|1rxk]], [[1kl4|1kl4]], [[1srf|1srf]], [[2rtq|2rtq]], [[2rte|2rte]], [[1swb|1swb]], [[1vwo|1vwo]], [[2rta|2rta]], [[2rtc|2rtc]], [[2rtn|2rtn]], [[1swo|1swo]], [[1swn|1swn]], [[1n7y|1n7y]], [[1vwp|1vwp]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KYT:(3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III)'>KYT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wpu RCSB], [http://www.ebi.ac.uk/pdbsum/2wpu PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpu OCA], [https://pdbe.org/2wpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpu RCSB], [https://www.ebi.ac.uk/pdbsum/2wpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpu ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wpu" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Avidin|Avidin]]
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*[[Avidin 3D structures|Avidin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: Creus, M.]]
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[[Category: Creus M]]
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[[Category: Gradinaru, J.]]
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[[Category: Gradinaru J]]
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[[Category: Heinisch, T.]]
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[[Category: Heinisch T]]
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[[Category: Sardo, A.]]
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[[Category: Sardo A]]
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[[Category: Schirmer, T.]]
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[[Category: Schirmer T]]
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[[Category: Ward, T R.]]
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[[Category: Ward TR]]
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[[Category: Wohlschlager, T.]]
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[[Category: Wohlschlager T]]
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[[Category: Zimbron, J M.]]
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[[Category: Zimbron JM]]
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[[Category: Biotin binding protein]]
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Current revision

Chaperoned ruthenium metallodrugs that recognize telomeric DNA

PDB ID 2wpu

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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