This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2xel

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:45, 17 January 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
==MOLECULAR MECHANISM OF PENTACHLOROPSEUDILIN MEDIATED INHIBITION OF MYOSIN MOTOR ACTIVITY==
+
 
-
<StructureSection load='2xel' size='340' side='right' caption='[[2xel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+
==Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity==
 +
<StructureSection load='2xel' size='340' side='right'caption='[[2xel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2xel]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEL FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2xel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEL FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=IA2:2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL'>IA2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mne|1mne]], [[1d1c|1d1c]], [[1jx2|1jx2]], [[1q5g|1q5g]], [[1w9l|1w9l]], [[1mmn|1mmn]], [[1d0y|1d0y]], [[1vom|1vom]], [[2aka|2aka]], [[2jhr|2jhr]], [[2jj9|2jj9]], [[1lvk|1lvk]], [[1w9j|1w9j]], [[1jwy|1jwy]], [[2x9h|2x9h]], [[1yv3|1yv3]], [[1fmv|1fmv]], [[1d0x|1d0x]], [[1fmw|1fmw]], [[1d1b|1d1b]], [[1g8x|1g8x]], [[1mma|1mma]], [[1d1a|1d1a]], [[1mmg|1mmg]], [[1w9i|1w9i]], [[1d0z|1d0z]], [[1mnd|1mnd]], [[1w9k|1w9k]], [[1mmd|1mmd]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=IA2:2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL'>IA2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xel OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xel RCSB], [http://www.ebi.ac.uk/pdbsum/2xel PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xel OCA], [https://pdbe.org/2xel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xel RCSB], [https://www.ebi.ac.uk/pdbsum/2xel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xel ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2xel" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Myosin|Myosin]]
+
*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
Line 23: Line 27:
</StructureSection>
</StructureSection>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
-
[[Category: Chinthalapudi, K.]]
+
[[Category: Large Structures]]
-
[[Category: Coluccio, L M.]]
+
[[Category: Chinthalapudi K]]
-
[[Category: Fedorov, R.]]
+
[[Category: Coluccio LM]]
-
[[Category: Gutzeit, H O.]]
+
[[Category: Fedorov R]]
-
[[Category: Hartmann, F K.]]
+
[[Category: Gutzeit HO]]
-
[[Category: Heissler, S M.]]
+
[[Category: Hartmann FK]]
-
[[Category: Knoelker, H J.]]
+
[[Category: Heissler SM]]
-
[[Category: Manstein, D J.]]
+
[[Category: Knoelker HJ]]
-
[[Category: Martin, R.]]
+
[[Category: Manstein DJ]]
-
[[Category: Taft, M H.]]
+
[[Category: Martin R]]
-
[[Category: Tsiavaliaris, G.]]
+
[[Category: Taft MH]]
-
[[Category: Allosteric inhibitor]]
+
[[Category: Tsiavaliaris G]]
-
[[Category: Contractile protein]]
+
-
[[Category: Motor protein]]
+
-
[[Category: Non-hydroylsable atp analogue]]
+

Current revision

Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity

PDB ID 2xel

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xel"
Personal tools