2xhd
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | == | + | |
| - | <StructureSection load='2xhd' size='340' side='right' caption='[[2xhd]], [[Resolution|resolution]] 1.80Å' scene=''> | + | ==Crystal structure of N-((2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H- inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human GluA2 receptor== |
| + | <StructureSection load='2xhd' size='340' side='right'caption='[[2xhd]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xhd]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xhd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XHD FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7T9:N-[(2S)-5-(6-FLUORO-3-PYRIDINYL)-2,3-DIHYDRO-1H-INDEN-2-YL]-2-PROPANESULFONAMIDE'>7T9</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7T9:N-[(2S)-5-(6-FLUORO-3-PYRIDINYL)-2,3-DIHYDRO-1H-INDEN-2-YL]-2-PROPANESULFONAMIDE'>7T9</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xhd OCA], [https://pdbe.org/2xhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xhd RCSB], [https://www.ebi.ac.uk/pdbsum/2xhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xhd ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xh/2xhd_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xh/2xhd_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xhd ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 25: | Line 26: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xhd" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 33: | Line 35: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Aldegheri | + | [[Category: Large Structures]] |
| - | [[Category: Andreotti | + | [[Category: Aldegheri L]] |
| - | [[Category: Ballantine | + | [[Category: Andreotti D]] |
| - | [[Category: Bax | + | [[Category: Ballantine S]] |
| - | [[Category: Harker | + | [[Category: Bax BD]] |
| - | [[Category: Harries | + | [[Category: Harker AJ]] |
| - | [[Category: Harris | + | [[Category: Harries M]] |
| - | [[Category: Lund | + | [[Category: Harris AJ]] |
| - | [[Category: Melarange | + | [[Category: Lund J]] |
| - | [[Category: Mingardi | + | [[Category: Melarange R]] |
| - | [[Category: Mookherjee | + | [[Category: Mingardi A]] |
| - | [[Category: Mosley | + | [[Category: Mookherjee C]] |
| - | [[Category: Neve | + | [[Category: Mosley J]] |
| - | [[Category: Oliosi | + | [[Category: Neve M]] |
| - | [[Category: Profeta | + | [[Category: Oliosi B]] |
| - | [[Category: Smith | + | [[Category: Profeta R]] |
| - | [[Category: Smith | + | [[Category: Smith KJ]] |
| - | [[Category: Spada | + | [[Category: Smith PW]] |
| - | [[Category: Thewlis | + | [[Category: Spada S]] |
| - | [[Category: Ward | + | [[Category: Thewlis KM]] |
| - | [[Category: Yusaf | + | [[Category: Ward SE]] |
| - | + | [[Category: Yusaf SP]] | |
| - | + | ||
Current revision
Crystal structure of N-((2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H- inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human GluA2 receptor
| |||||||||||
Categories: Homo sapiens | Large Structures | Aldegheri L | Andreotti D | Ballantine S | Bax BD | Harker AJ | Harries M | Harris AJ | Lund J | Melarange R | Mingardi A | Mookherjee C | Mosley J | Neve M | Oliosi B | Profeta R | Smith KJ | Smith PW | Spada S | Thewlis KM | Ward SE | Yusaf SP
