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2w9u
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2w9u' size='340' side='right' caption='[[2w9u | + | ==Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii== |
| + | <StructureSection load='2w9u' size='340' side='right'caption='[[2w9u]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2w9u]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2w9u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9U FirstGlance]. <br> |
| - | </td></tr><tr | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9u OCA], [https://pdbe.org/2w9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9u RCSB], [https://www.ebi.ac.uk/pdbsum/2w9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9u ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/DIS_PROJR DIS_PROJR] Recombinant protein inhibits the adhesion of alpha-1/beta-1-K562 (ITGA1/ITGB1) cells to collagen IV with an IC(50) of 80 nM.<ref>PMID:16215260</ref> <ref>PMID:21656569</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9u_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9u_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9u ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2w9u" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Protobothrops jerdonii]] | [[Category: Protobothrops jerdonii]] | ||
| - | [[Category: Calvete | + | [[Category: Calvete JJ]] |
| - | [[Category: Carbajo | + | [[Category: Carbajo RJ]] |
| - | [[Category: Mosulen | + | [[Category: Mosulen S]] |
| - | [[Category: Pineda-Lucena | + | [[Category: Pineda-Lucena A]] |
| - | [[Category: Sanz | + | [[Category: Sanz L]] |
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Current revision
Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii
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