3b2m

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==Crystal Structure of the Major Pilin from Streptococcus pyogenes==
==Crystal Structure of the Major Pilin from Streptococcus pyogenes==
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<StructureSection load='3b2m' size='340' side='right' caption='[[3b2m]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
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<StructureSection load='3b2m' size='340' side='right'caption='[[3b2m]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3b2m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_m1 Streptococcus pyogenes serotype m1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B2M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3b2m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_M1 Streptococcus pyogenes serotype M1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B2M FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spy0128 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=301447 Streptococcus pyogenes serotype M1])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b2m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b2m RCSB], [http://www.ebi.ac.uk/pdbsum/3b2m PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b2m OCA], [https://pdbe.org/3b2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b2m RCSB], [https://www.ebi.ac.uk/pdbsum/3b2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b2m ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PILIN_STRP1 PILIN_STRP1] Major component of the pilus. A stack of the pilin subunits, joined by intermolecular isopeptide bonds, forms the pilus. The pilus is required for bacterial adhesion to host cells, for bacterial aggregation, and for biofilm formation.<ref>PMID:17501921</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/3b2m_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/3b2m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b2m ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3b2m" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Pilin 3D structures|Pilin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptococcus pyogenes serotype m1]]
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[[Category: Large Structures]]
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[[Category: Baker, E N.]]
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[[Category: Streptococcus pyogenes serotype M1]]
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[[Category: Coulibaly, F.]]
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[[Category: Baker EN]]
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[[Category: Kang, H J.]]
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[[Category: Coulibaly F]]
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[[Category: Proft, T.]]
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[[Category: Kang HJ]]
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[[Category: All-beta]]
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[[Category: Proft T]]
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[[Category: Cell adhesion]]
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[[Category: Isopeptide]]
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[[Category: Pili]]
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[[Category: Structural protein]]
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Current revision

Crystal Structure of the Major Pilin from Streptococcus pyogenes

PDB ID 3b2m

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