3a2e
From Proteopedia
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==Crystal structure of ginkbilobin-2, the novel antifungal protein from Ginkgo biloba seeds== | ==Crystal structure of ginkbilobin-2, the novel antifungal protein from Ginkgo biloba seeds== | ||
| - | <StructureSection load='3a2e' size='340' side='right' caption='[[3a2e]], [[Resolution|resolution]] 2.38Å' scene=''> | + | <StructureSection load='3a2e' size='340' side='right'caption='[[3a2e]], [[Resolution|resolution]] 2.38Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3a2e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3a2e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ginbi Ginbi]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2e79 2e79]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3A2E FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3a2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2e OCA], [http://pdbe.org/3a2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a2e RCSB], [http://www.ebi.ac.uk/pdbsum/3a2e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2e ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GNK2_GINBI GNK2_GINBI]] Possesses antifungal activity against F.oxysporum, T.reesei and C.albicans. Weakly inhibits the aspartic acid protease pepsin activity.<ref>PMID:17338634</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2e_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2e_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a2e ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Ginbi]] |
| - | [[Category: Hatano, K | + | [[Category: Large Structures]] |
| - | [[Category: Miyakawa, T | + | [[Category: Hatano, K]] |
| - | [[Category: Miyazono, K | + | [[Category: Miyakawa, T]] |
| - | [[Category: Sawano, Y | + | [[Category: Miyazono, K]] |
| - | [[Category: Tanokura, M | + | [[Category: Sawano, Y]] |
| + | [[Category: Tanokura, M]] | ||
[[Category: Antifungal protein]] | [[Category: Antifungal protein]] | ||
[[Category: C-x8-c-x2-c motif]] | [[Category: C-x8-c-x2-c motif]] | ||
[[Category: Plant protein]] | [[Category: Plant protein]] | ||
Current revision
Crystal structure of ginkbilobin-2, the novel antifungal protein from Ginkgo biloba seeds
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