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2zwi

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==Crystal structure of alpha/beta-Galactoside alpha-2,3-Sialyltransferase from a Luminous Marine Bacterium, <I>Photobacterium phosphoreum</I>==
==Crystal structure of alpha/beta-Galactoside alpha-2,3-Sialyltransferase from a Luminous Marine Bacterium, <I>Photobacterium phosphoreum</I>==
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<StructureSection load='2zwi' size='340' side='right' caption='[[2zwi]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='2zwi' size='340' side='right'caption='[[2zwi]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zwi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Photobacterium_phosphoreum Photobacterium phosphoreum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZWI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zwi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Photobacterium_phosphoreum Photobacterium phosphoreum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZWI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pst3-467 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=659 Photobacterium phosphoreum])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactoside_alpha-2,3-sialyltransferase Beta-galactoside alpha-2,3-sialyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.99.4 2.4.99.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zwi OCA], [https://pdbe.org/2zwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zwi RCSB], [https://www.ebi.ac.uk/pdbsum/2zwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zwi ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zwi RCSB], [http://www.ebi.ac.uk/pdbsum/2zwi PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/A5LHX0_PHOPO A5LHX0_PHOPO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zw/2zwi_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zw/2zwi_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zwi ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2zwi" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Sialyltransferase 3D structures|Sialyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-galactoside alpha-2,3-sialyltransferase]]
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[[Category: Large Structures]]
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[[Category: Photobacterium phosphoreum]]
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[[Category: Ichikawa, M.]]
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[[Category: Ito, M.]]
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[[Category: Iwatani, T.]]
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[[Category: Kajiwara, H.]]
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[[Category: Kakuta, Y.]]
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[[Category: Kimura, M.]]
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[[Category: Okino, N.]]
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[[Category: Sakakura, M.]]
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[[Category: Takakura, Y.]]
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[[Category: Yamamoto, T.]]
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[[Category: 3-sialyltransfease]]
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[[Category: Alpha-2]]
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[[Category: Glycosyltransferase]]
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[[Category: Jt-ish-467]]
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[[Category: Photobacterium phosphoreum]]
[[Category: Photobacterium phosphoreum]]
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[[Category: Transferase]]
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[[Category: Ichikawa M]]
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[[Category: Ito M]]
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[[Category: Iwatani T]]
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[[Category: Kajiwara H]]
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[[Category: Kakuta Y]]
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[[Category: Kimura M]]
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[[Category: Okino N]]
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[[Category: Sakakura M]]
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[[Category: Takakura Y]]
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[[Category: Yamamoto T]]

Current revision

Crystal structure of alpha/beta-Galactoside alpha-2,3-Sialyltransferase from a Luminous Marine Bacterium, Photobacterium phosphoreum

PDB ID 2zwi

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