This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2v4e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:05, 13 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
==A NON-CYTOTOXIC DSRED VARIANT FOR WHOLE-CELL LABELING==
+
 
-
<StructureSection load='2v4e' size='340' side='right' caption='[[2v4e]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+
==A non-cytotoxic DsRed variant for whole-cell labeling==
 +
<StructureSection load='2v4e' size='340' side='right'caption='[[2v4e]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2v4e]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Discosoma_sp. Discosoma sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4E FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2v4e]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Discosoma_sp. Discosoma sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4E FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vae|2vae]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRQ:{(4Z)-4-(4-HYDROXYBENZYLIDENE)-2-[3-(METHYLTHIO)PROPANIMIDOYL]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>NRQ</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4e RCSB], [http://www.ebi.ac.uk/pdbsum/2v4e PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4e OCA], [https://pdbe.org/2v4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4e RCSB], [https://www.ebi.ac.uk/pdbsum/2v4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4e ProSAT]</span></td></tr>
-
<table>
+
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4e_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4e_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v4e ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 25: Line 26:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2v4e" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Green Fluorescent Protein|Green Fluorescent Protein]]
+
*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Discosoma sp.]]
+
[[Category: Discosoma sp]]
-
[[Category: Berman, A.]]
+
[[Category: Large Structures]]
-
[[Category: Bhattacharyya, D.]]
+
[[Category: Berman A]]
-
[[Category: Broxmeyer, H E.]]
+
[[Category: Bhattacharyya D]]
-
[[Category: Glick, B S.]]
+
[[Category: Broxmeyer HE]]
-
[[Category: Keenan, R J.]]
+
[[Category: Glick BS]]
-
[[Category: Strack, R L.]]
+
[[Category: Keenan RJ]]
-
[[Category: Strongin, D E.]]
+
[[Category: Strack RL]]
-
[[Category: Tao, W.]]
+
[[Category: Strongin DE]]
-
[[Category: Chromophore]]
+
[[Category: Tao W]]
-
[[Category: Dsred]]
+
-
[[Category: Fluorescent protein]]
+
-
[[Category: Luminescence]]
+
-
[[Category: Photoprotein]]
+

Current revision

A non-cytotoxic DsRed variant for whole-cell labeling

PDB ID 2v4e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools