This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ji4
From Proteopedia
(Difference between revisions)
| (19 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2ji4.gif|left|200px]]<br /> | ||
| - | <applet load="2ji4" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2ji4, resolution 2.55Å" /> | ||
| - | '''HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE- ASSOCIATED PROTEIN 41 (PAP41)'''<br /> | ||
| - | == | + | ==Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41)== |
| - | + | <StructureSection load='2ji4' size='340' side='right'caption='[[2ji4]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2ji4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JI4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ji4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ji4 OCA], [https://pdbe.org/2ji4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ji4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ji4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ji4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KPRB_HUMAN KPRB_HUMAN] Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2ji4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ji4 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | + | [[Category: Berglund H]] | |
| - | [[Category: Berglund | + | [[Category: Busam R]] |
| - | [[Category: Busam | + | [[Category: Collins R]] |
| - | [[Category: Collins | + | [[Category: Dahlgren LG]] |
| - | [[Category: Dahlgren | + | [[Category: Edwards A]] |
| - | [[Category: Edwards | + | [[Category: Flodin S]] |
| - | [[Category: Flodin | + | [[Category: Flores A]] |
| - | [[Category: Flores | + | [[Category: Graslund S]] |
| - | [[Category: Graslund | + | [[Category: Hallberg BM]] |
| - | [[Category: Hallberg | + | [[Category: Hammarstrom M]] |
| - | [[Category: Hammarstrom | + | [[Category: Holmberg-Schiavone L]] |
| - | [[Category: Holmberg-Schiavone | + | [[Category: Johansson I]] |
| - | [[Category: Johansson | + | [[Category: Karlberg T]] |
| - | [[Category: Karlberg | + | [[Category: Kotenyova T]] |
| - | [[Category: Kotenyova | + | [[Category: Lehtio L]] |
| - | [[Category: Lehtio | + | [[Category: Moche M]] |
| - | [[Category: Moche | + | [[Category: Nordlund P]] |
| - | [[Category: Nordlund | + | [[Category: Nyman T]] |
| - | [[Category: Nyman | + | [[Category: Ogg D]] |
| - | [[Category: Ogg | + | [[Category: Persson C]] |
| - | [[Category: Persson | + | [[Category: Sagemark J]] |
| - | [[Category: Sagemark | + | [[Category: Stenmark P]] |
| - | [[Category: Stenmark | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Thorsell AG]] |
| - | [[Category: Thorsell | + | [[Category: Van Den Berg S]] |
| - | [[Category: | + | [[Category: Weigelt J]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41)
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith C | Berglund H | Busam R | Collins R | Dahlgren LG | Edwards A | Flodin S | Flores A | Graslund S | Hallberg BM | Hammarstrom M | Holmberg-Schiavone L | Johansson I | Karlberg T | Kotenyova T | Lehtio L | Moche M | Nordlund P | Nyman T | Ogg D | Persson C | Sagemark J | Stenmark P | Sundstrom M | Thorsell AG | Van Den Berg S | Weigelt J
