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2iey
From Proteopedia
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==Crystal Structure of mouse Rab27b bound to GDP in hexagonal space group== | ==Crystal Structure of mouse Rab27b bound to GDP in hexagonal space group== | ||
| - | <StructureSection load='2iey' size='340' side='right' caption='[[2iey]], [[Resolution|resolution]] 3.18Å' scene=''> | + | <StructureSection load='2iey' size='340' side='right'caption='[[2iey]], [[Resolution|resolution]] 3.18Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2iey]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2iey]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IEY FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iez|2iez]], [[2if0|2if0]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2iez|2iez]], [[2if0|2if0]]</div></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Small_monomeric_GTPase Small monomeric GTPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.2 3.6.5.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iey OCA], [https://pdbe.org/2iey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iey RCSB], [https://www.ebi.ac.uk/pdbsum/2iey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iey ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/RB27B_MOUSE RB27B_MOUSE]] May be involved in targeting uroplakins to urothelial apical membranes (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iey_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iey_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iey ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2iey" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Lk3 transgenic mice]] | ||
[[Category: Small monomeric GTPase]] | [[Category: Small monomeric GTPase]] | ||
| - | [[Category: Chavas, L M.G | + | [[Category: Chavas, L M.G]] |
| - | [[Category: Ihara, K | + | [[Category: Ihara, K]] |
| - | [[Category: Izumi, T | + | [[Category: Izumi, T]] |
| - | [[Category: Kamikubo, H | + | [[Category: Kamikubo, H]] |
| - | [[Category: Kataoka, M | + | [[Category: Kataoka, M]] |
| - | [[Category: Kato, R | + | [[Category: Kato, R]] |
| - | [[Category: Kawasaki, M | + | [[Category: Kawasaki, M]] |
| - | [[Category: Torii, S | + | [[Category: Torii, S]] |
| - | [[Category: Wakatsuki, S | + | [[Category: Wakatsuki, S]] |
[[Category: Gdp]] | [[Category: Gdp]] | ||
[[Category: Gtpase]] | [[Category: Gtpase]] | ||
Current revision
Crystal Structure of mouse Rab27b bound to GDP in hexagonal space group
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Categories: Large Structures | Lk3 transgenic mice | Small monomeric GTPase | Chavas, L M.G | Ihara, K | Izumi, T | Kamikubo, H | Kataoka, M | Kato, R | Kawasaki, M | Torii, S | Wakatsuki, S | Gdp | Gtpase | Rab | Rab27 | Signaling protein | Swapping

