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3wqu

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==Staphylococcus aureus FtsA complexed with ATP==
==Staphylococcus aureus FtsA complexed with ATP==
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<StructureSection load='3wqu' size='340' side='right' caption='[[3wqu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3wqu' size='340' side='right'caption='[[3wqu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wqu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WQU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wqu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WQU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wqt|3wqt]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wqu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wqu RCSB], [http://www.ebi.ac.uk/pdbsum/3wqu PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wqu OCA], [https://pdbe.org/3wqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wqu RCSB], [https://www.ebi.ac.uk/pdbsum/3wqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wqu ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/FTSA_STAAR FTSA_STAAR] This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity).
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The bacterial cell-division protein FtsA anchors FtsZ to the cytoplasmic membrane. But how FtsA and FtsZ interact during membrane division remains obscure. We have solved 2.2 A resolution crystal structure for FtsA from Staphylococcus aureus. In the crystals, SaFtsA molecules within the dimer units are twisted, in contrast to the straight filament of FtsA from Thermotoga maritima, and the half of S12-S13 hairpin regions are disordered. We confirmed that SaFtsZ and SaFtsA associate in vitro, and found that SaFtsZ GTPase activity is enhanced by interaction with SaFtsA.
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Crystal structure of FtsA from Staphylococcus aureus.,Fujita J, Maeda Y, Nagao C, Tsuchiya Y, Miyazaki Y, Hirose M, Mizohata E, Matsumoto Y, Inoue T, Mizuguchi K, Matsumura H FEBS Lett. 2014 May 21;588(10):1879-85. doi: 10.1016/j.febslet.2014.04.008. Epub , 2014 Apr 18. PMID:24746687<ref>PMID:24746687</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fujita, J.]]
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[[Category: Large Structures]]
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[[Category: Inoue, T.]]
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[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
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[[Category: Maeda, Y.]]
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[[Category: Fujita J]]
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[[Category: Matsumura, H.]]
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[[Category: Inoue T]]
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[[Category: Miyazaki, Y.]]
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[[Category: Maeda Y]]
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[[Category: Actin-like fold]]
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[[Category: Matsumura H]]
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[[Category: Structural genomic]]
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[[Category: Miyazaki Y]]

Current revision

Staphylococcus aureus FtsA complexed with ATP

PDB ID 3wqu

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