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2d9d
From Proteopedia
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==Solution structure of the BAG domain (275-350) of BAG-family molecular chaperone regulator-5== | ==Solution structure of the BAG domain (275-350) of BAG-family molecular chaperone regulator-5== | ||
| - | <StructureSection load='2d9d' size='340' side='right' caption='[[2d9d | + | <StructureSection load='2d9d' size='340' side='right'caption='[[2d9d]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2d9d]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2d9d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D9D FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d9d OCA], [https://pdbe.org/2d9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d9d RCSB], [https://www.ebi.ac.uk/pdbsum/2d9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d9d ProSAT], [https://www.topsan.org/Proteins/RSGI/2d9d TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BAG5_HUMAN BAG5_HUMAN] Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.<ref>PMID:20223214</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2d9d" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[BAG | + | *[[BAG family proteins 3D structures|BAG family proteins 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hatta R]] |
| - | [[Category: | + | [[Category: Hayashi F]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
| - | [[Category: Yoshida | + | [[Category: Yoshida M]] |
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Current revision
Solution structure of the BAG domain (275-350) of BAG-family molecular chaperone regulator-5
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