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1ug7

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==Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806==
==Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806==
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<StructureSection load='1ug7' size='340' side='right' caption='[[1ug7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1ug7' size='340' side='right'caption='[[1ug7]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ug7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UG7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ug7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UG7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610208M17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ug7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ug7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ug7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ug7 PDBsum], [http://www.topsan.org/Proteins/RSGI/1ug7 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ug7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ug7 OCA], [https://pdbe.org/1ug7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ug7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ug7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ug7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ug7 TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AIDA_MOUSE AIDA_MOUSE] Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Aoki, M.]]
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[[Category: Aoki M]]
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[[Category: Arakawa, T.]]
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[[Category: Arakawa T]]
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[[Category: Carninci, P.]]
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[[Category: Carninci P]]
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[[Category: Hayashizaki, Y.]]
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[[Category: Hayashizaki Y]]
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[[Category: Hirota, H.]]
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[[Category: Hirota H]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kawai, J.]]
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[[Category: Kawai J]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba S]]
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[[Category: Li, H.]]
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[[Category: Li H]]
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[[Category: Matsuda, T.]]
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[[Category: Matsuda T]]
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[[Category: Osanai, T.]]
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[[Category: Osanai T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Seki E]]
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[[Category: Seki, E.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Tanaka A]]
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[[Category: Tanaka, A.]]
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[[Category: Terada M]]
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[[Category: Terada, M.]]
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[[Category: Tomizawa T]]
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[[Category: Tomizawa, T.]]
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[[Category: Yabuki T]]
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[[Category: Yabuki, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Yoshida M]]
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[[Category: Yoshida, M.]]
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[[Category: Four helical up-and-down bundle]]
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[[Category: Hypothetical protein flj12806]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806

PDB ID 1ug7

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