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2o2l

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==Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog==
==Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog==
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<StructureSection load='2o2l' size='340' side='right' caption='[[2o2l]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
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<StructureSection load='2o2l' size='340' side='right'caption='[[2o2l]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2o2l]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O2L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2o2l]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O2L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nzg|2nzg]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o2l RCSB], [http://www.ebi.ac.uk/pdbsum/2o2l PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o2l OCA], [https://pdbe.org/2o2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o2l RCSB], [https://www.ebi.ac.uk/pdbsum/2o2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o2l ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ELBH_ECOLX ELBH_ECOLX] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2o2l" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Askarieh, G.]]
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[[Category: Large Structures]]
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[[Category: Holmner, A.]]
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[[Category: Askarieh G]]
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[[Category: Krengel, U.]]
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[[Category: Holmner A]]
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[[Category: Okvist, M.]]
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[[Category: Krengel U]]
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[[Category: Blood group antigen]]
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[[Category: Okvist M]]
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[[Category: Enterotoxigenic e. coli]]
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[[Category: Heat-labile enterotoxin]]
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[[Category: Toxin]]
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Current revision

Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog

PDB ID 2o2l

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