We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
4woz
From Proteopedia
(Difference between revisions)
m (Protected "4woz" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine== | |
| + | <StructureSection load='4woz' size='340' side='right'caption='[[4woz]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4woz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile Clostridioides difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WOZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN9:2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE'>MN9</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4woz OCA], [https://pdbe.org/4woz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4woz RCSB], [https://www.ebi.ac.uk/pdbsum/4woz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4woz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D5Q364_CLODI D5Q364_CLODI] Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.[HAMAP-Rule:MF_01237] | ||
| - | + | ==See Also== | |
| - | + | *[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Clostridioides difficile]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Cui YF]] | ||
| + | [[Category: Guo RT]] | ||
| + | [[Category: Liu WD]] | ||
| + | [[Category: Wu QQ]] | ||
| + | [[Category: Zhu DM]] | ||
Current revision
Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
| |||||||||||
Categories: Clostridioides difficile | Large Structures | Chen X | Cui YF | Guo RT | Liu WD | Wu QQ | Zhu DM
