4k6u

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==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386==
==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386==
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<StructureSection load='4k6u' size='340' side='right' caption='[[4k6u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4k6u' size='340' side='right'caption='[[4k6u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k6u]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k6u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D37 Human adenovirus D37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k6t|4k6t]], [[4k6v|4k6v]], [[4k6w|4k6w]], [[3n0i|3n0i]], [[3qnd|3qnd]], [[1uxe|1uxe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6u RCSB], [http://www.ebi.ac.uk/pdbsum/4k6u PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6u OCA], [https://pdbe.org/4k6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6u RCSB], [https://www.ebi.ac.uk/pdbsum/4k6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6u ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q64823_9ADEN Q64823_9ADEN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bauer, J.]]
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[[Category: Human adenovirus D37]]
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[[Category: Stehle, T.]]
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[[Category: Large Structures]]
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[[Category: Adenovirus]]
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[[Category: Bauer J]]
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[[Category: Carbohydrate mimic]]
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[[Category: Stehle T]]
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[[Category: Fiber knob]]
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[[Category: Multivalent ligand]]
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[[Category: Protein carbohydrate interaction]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386

PDB ID 4k6u

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