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2xkj
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| - | ==CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)== | + | |
| - | <StructureSection load='2xkj' size='340' side='right' caption='[[2xkj]], [[Resolution|resolution]] 2.20Å' scene=''> | + | ==CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE)== |
| + | <StructureSection load='2xkj' size='340' side='right'caption='[[2xkj]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xkj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XKJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xkj OCA], [https://pdbe.org/2xkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xkj RCSB], [https://www.ebi.ac.uk/pdbsum/2xkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xkj ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B0V9T6_ACIBY B0V9T6_ACIBY] [https://www.uniprot.org/uniprot/B0VP98_ACIBS B0VP98_ACIBS] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[HAMAP-Rule:MF_00936] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/2xkj_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/2xkj_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xkj ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xkj" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Topoisomerase|Topoisomerase]] | + | *[[Topoisomerase 3D structures|Topoisomerase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acinetobacter baumannii]] | [[Category: Acinetobacter baumannii]] | ||
| - | [[Category: Bax | + | [[Category: Large Structures]] |
| - | [[Category: Chan | + | [[Category: Bax BD]] |
| - | [[Category: Fosberry | + | [[Category: Chan PF]] |
| - | [[Category: Gwynn | + | [[Category: Fosberry AP]] |
| - | [[Category: Homes | + | [[Category: Gwynn MN]] |
| - | [[Category: Huang | + | [[Category: Homes P]] |
| - | [[Category: Kranz | + | [[Category: Huang J]] |
| - | [[Category: Leydon | + | [[Category: Kranz M]] |
| - | [[Category: Miles | + | [[Category: Leydon VR]] |
| - | [[Category: Pearson | + | [[Category: Miles TJ]] |
| - | [[Category: Perera | + | [[Category: Pearson ND]] |
| - | [[Category: Shillings | + | [[Category: Perera RL]] |
| - | [[Category: Wohlkonig | + | [[Category: Shillings AJ]] |
| - | + | [[Category: Wohlkonig A]] | |
| - | + | ||
Current revision
CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE)
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Categories: Acinetobacter baumannii | Large Structures | Bax BD | Chan PF | Fosberry AP | Gwynn MN | Homes P | Huang J | Kranz M | Leydon VR | Miles TJ | Pearson ND | Perera RL | Shillings AJ | Wohlkonig A
