4wpu
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4wpu is ON HOLD until Paper Publication Authors: Kim, H.L., Sacchettini, J.C. Description: Crystal Structure of E83A mutant of Mtb PEPCK in complex...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP== | |
| + | <StructureSection load='4wpu' size='340' side='right'caption='[[4wpu]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4wpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WPU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpu OCA], [https://pdbe.org/4wpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wpu RCSB], [https://www.ebi.ac.uk/pdbsum/4wpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | ||
| - | + | ==See Also== | |
| - | + | *[[Phosphoenolpyruvate carboxykinase 3D structures|Phosphoenolpyruvate carboxykinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Ra]] | ||
| + | [[Category: Kim HL]] | ||
| + | [[Category: Sacchettini JC]] | ||
Current revision
Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP
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