2mw2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Hha-H-NS46 charge zipper complex== | |
| - | + | <StructureSection load='2mw2' size='340' side='right'caption='[[2mw2]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mw2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MW2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mw2 OCA], [https://pdbe.org/2mw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mw2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HHA_ECOLI HHA_ECOLI] Down-regulates hemolysin production and can also stimulate transposition events in vivo. Binds DNA and influences DNA topology in response to environmental stimuli. Involved in persister cell formation, acting downstream of mRNA interferase (toxin) MqsR. Decreases biofilm formation by repressing the transcription of fimbrial genes fimA and ihfA, and by repressing the transcription of tRNAs corresponding to rare codons, which are abundant in type 1 fimbrial genes.<ref>PMID:1956303</ref> <ref>PMID:16317765</ref> <ref>PMID:18545668</ref> <ref>PMID:19909729</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bernado P]] | ||
| + | [[Category: Cordeiro TN]] | ||
| + | [[Category: Garcia J]] | ||
| + | [[Category: Millet O]] | ||
| + | [[Category: Pons M]] | ||
Current revision
Hha-H-NS46 charge zipper complex
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