4whg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:01, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4whg is ON HOLD until Paper Publication
+
==Crystal Structure of TR3 LBD in complex with Molecule 3==
-
 
+
<StructureSection load='4whg' size='340' side='right'caption='[[4whg]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
-
Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Wang, Y., Hou, P.P., Wu, Q., Lin, T.W.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4whg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WHG FirstGlance]. <br>
-
Description: Crystal Structure of TR3 LBD in complex with Molecule 3
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3NB:1-(3,4,5-TRIHYDROXYPHENYL)OCTAN-1-ONE'>3NB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4whg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whg OCA], [https://pdbe.org/4whg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4whg RCSB], [https://www.ebi.ac.uk/pdbsum/4whg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4whg ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Cai QX]]
 +
[[Category: Hou PP]]
 +
[[Category: Li AZ]]
 +
[[Category: Li FW]]
 +
[[Category: Lin TW]]
 +
[[Category: Tian XY]]
 +
[[Category: Wang WJ]]
 +
[[Category: Wang Y]]
 +
[[Category: Wu Q]]

Current revision

Crystal Structure of TR3 LBD in complex with Molecule 3

PDB ID 4whg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4whg"
Personal tools