1kag

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[[Image:1kag.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)==
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|PDB= 1kag |SIZE=350|CAPTION= <scene name='initialview01'>1kag</scene>, resolution 2.05&Aring;
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<StructureSection load='1kag' size='340' side='right'caption='[[1kag]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1kag]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KAG FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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|GENE= AROK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kag OCA], [https://pdbe.org/1kag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kag RCSB], [https://www.ebi.ac.uk/pdbsum/1kag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kag ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1kag TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROK_ECOLI AROK_ECOLI] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<ref>PMID:1309529</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1kag_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kag ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)'''
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==See Also==
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*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1KAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAG OCA].
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__TOC__
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</StructureSection>
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==Reference==
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Crystal structure of the Escherichia coli shikimate kinase I (AroK) that confers sensitivity to mecillinam., Romanowski MJ, Burley SK, Proteins. 2002 Jun 1;47(4):558-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12001235 12001235]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Shikimate kinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Romanowski MJ]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Romanowski, M J.]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:14:43 2008''
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Current revision

Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)

PDB ID 1kag

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