3cxg
From Proteopedia
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==Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w== | ==Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w== | ||
| - | <StructureSection load='3cxg' size='340' side='right' caption='[[3cxg]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3cxg' size='340' side='right'caption='[[3cxg]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cxg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3cxg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxg OCA], [https://pdbe.org/3cxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxg RCSB], [https://www.ebi.ac.uk/pdbsum/3cxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxg ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THIO3_PLAF7 THIO3_PLAF7] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.<ref>PMID:16910770</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/3cxg_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/3cxg_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cxg ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Plasmodium falciparum]] | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Plasmodium falciparum 3D7]] |
| - | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Cossar | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Cossar D]] |
| - | [[Category: Hills | + | [[Category: Edwards AM]] |
| - | [[Category: Hui | + | [[Category: Hills T]] |
| - | [[Category: Kozieradzki | + | [[Category: Hui R]] |
| - | [[Category: Lew | + | [[Category: Kozieradzki I]] |
| - | [[Category: Pizarro | + | [[Category: Lew J]] |
| - | + | [[Category: Pizarro J]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont AK]] |
| - | [[Category: Wilkstrom | + | [[Category: Wilkstrom M]] |
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Current revision
Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w
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Categories: Large Structures | Plasmodium falciparum 3D7 | Arrowsmith CH | Bochkarev A | Bountra C | Cossar D | Edwards AM | Hills T | Hui R | Kozieradzki I | Lew J | Pizarro J | Schapira M | Wernimont AK | Wilkstrom M
