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3aiz

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==Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)==
==Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)==
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<StructureSection load='3aiz' size='340' side='right' caption='[[3aiz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3aiz' size='340' side='right'caption='[[3aiz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3aiz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AIZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3aiz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AIZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3aix|3aix]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">st0397 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 Sulfolobus tokodaii]), st0944 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 Sulfolobus tokodaii])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiz OCA], [https://pdbe.org/3aiz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aiz RCSB], [https://www.ebi.ac.uk/pdbsum/3aiz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aiz RCSB], [http://www.ebi.ac.uk/pdbsum/3aiz PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PCNA2_SULTO PCNA2_SULTO] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Both trimeric complexes inhibit DNA ligase and both 3'-5' and 5'-3' activity of Hel308 (Hjm) helicase, but stimulate Hjc, the Holliday junction cleavage enzyme.[HAMAP-Rule:MF_00317]<ref>PMID:18782564</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3aiz" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]]
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*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Sulfolobus tokodaii]]
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[[Category: Large Structures]]
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[[Category: Higuchi, S.]]
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[[Category: Sulfurisphaera tokodaii str. 7]]
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[[Category: Kawai, A.]]
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[[Category: Higuchi S]]
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[[Category: Miyamoto, S.]]
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[[Category: Kawai A]]
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[[Category: Protein-protein complex]]
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[[Category: Miyamoto S]]
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[[Category: Replication]]
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Current revision

Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)

PDB ID 3aiz

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