3cu5
From Proteopedia
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==Crystal structure of a two component transcriptional regulator AraC from Clostridium phytofermentans ISDg== | ==Crystal structure of a two component transcriptional regulator AraC from Clostridium phytofermentans ISDg== | ||
| - | <StructureSection load='3cu5' size='340' side='right' caption='[[3cu5]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='3cu5' size='340' side='right'caption='[[3cu5]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cu5]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3cu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lachnoclostridium_phytofermentans_ISDg Lachnoclostridium phytofermentans ISDg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CU5 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cu5 OCA], [https://pdbe.org/3cu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cu5 RCSB], [https://www.ebi.ac.uk/pdbsum/3cu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cu5 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3cu5 TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A9KIW7_LACP7 A9KIW7_LACP7] May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.[ARBA:ARBA00024867] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cu5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cu5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cu5 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Lachnoclostridium phytofermentans ISDg]] |
| - | [[Category: Meyer | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Burley SK]] |
| + | [[Category: Malashkevich VN]] | ||
| + | [[Category: Meyer A]] | ||
| + | [[Category: Sauder JM]] | ||
| + | [[Category: Toro R]] | ||
| + | [[Category: Wasserman SR]] | ||
Current revision
Crystal structure of a two component transcriptional regulator AraC from Clostridium phytofermentans ISDg
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