1kuu

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[[Image:1kuu.jpg|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD==
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|PDB= 1kuu |SIZE=350|CAPTION= <scene name='initialview01'>1kuu</scene>, resolution 2.20&Aring;
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<StructureSection load='1kuu' size='340' side='right'caption='[[1kuu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1kuu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter Methanothermobacter]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KUU FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE= MTH1020 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145260 Methanothermobacter])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kuu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kuu OCA], [https://pdbe.org/1kuu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kuu RCSB], [https://www.ebi.ac.uk/pdbsum/1kuu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kuu ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD'''
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[https://www.uniprot.org/uniprot/PURO_METTH PURO_METTH] Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1KUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter Methanothermobacter]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KUU OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/1kuu_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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Crystal structure of Methanobacterium thermoautotrophicum conserved protein MTH1020 reveals an NTN-hydrolase fold., Saridakis V, Christendat D, Thygesen A, Arrowsmith CH, Edwards AM, Pai EF, Proteins. 2002 Jul 1;48(1):141-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12012346 12012346]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kuu ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanothermobacter]]
[[Category: Methanothermobacter]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Christendat D]]
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[[Category: Christendat, D.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Pai EF]]
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[[Category: Pai, E F.]]
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[[Category: Saridakis V]]
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[[Category: Saridakis, V.]]
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[[Category: Thygesen A]]
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[[Category: Thygesen, A.]]
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[[Category: conserved protein]]
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[[Category: ntn-hydrolase fold]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:22:25 2008''
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Current revision

CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD

PDB ID 1kuu

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