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4mwz

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==Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine==
==Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine==
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<StructureSection load='4mwz' size='340' side='right' caption='[[4mwz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='4mwz' size='340' side='right'caption='[[4mwz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mwz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MWZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mwz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax_Sal-1 Plasmodium vivax Sal-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MWZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iv0|4iv0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mwz RCSB], [http://www.ebi.ac.uk/pdbsum/4mwz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwz OCA], [https://pdbe.org/4mwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mwz RCSB], [https://www.ebi.ac.uk/pdbsum/4mwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mwz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A5K867_PLAVS A5K867_PLAVS]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lukk, T]]
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[[Category: Large Structures]]
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[[Category: Nair, S K]]
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[[Category: Plasmodium vivax Sal-1]]
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[[Category: Rossmann fold]]
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[[Category: Lukk T]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Nair SK]]

Current revision

Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine

PDB ID 4mwz

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