Lysin

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(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...)
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==Your Heading Here (maybe something like 'Structure')==
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<StructureSection load='' size='340' side='right' caption='Abalone lysin (PDB code [[1lis]])' scene='60/607850/Lysin_fertilization_protein/1'>
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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This is a default text for your page '''Carmit Gineisn/Test page'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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== Disease ==
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'''Lysin''' (Lys) is a protein which cleaves cell walls. Egg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.
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== Relevance ==
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== Structural highlights ==
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The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. <scene name='60/607850/Alpha_helixes/1'>To see alpha helixes press here</scene>. you can see the alpha helixes in pink. <scene name='60/607850/Surface/1'>the surface of the protein</scene> exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of <scene name='60/607850/Aromatic_and_aliphatic/1'>aromatic and aliphatic amino acids</scene>,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action<ref>PMID:8266073</ref>.
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== Structural highlights ==
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== 3D structure of lysin ==
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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[[Lysin 3D structures]]
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>
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[[Category:Topic Page]]

Current revision

Abalone lysin (PDB code 1lis)

Drag the structure with the mouse to rotate

References

  1. ↑ Shaw A, McRee DE, Vacquier VD, Stout CD. The crystal structure of lysin, a fertilization protein. Science. 1993 Dec 17;262(5141):1864-7. PMID:8266073
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