4tr7
From Proteopedia
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==Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis== | ==Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis== | ||
- | <StructureSection load='4tr7' size='340' side='right' caption='[[4tr7]], [[Resolution|resolution]] 2.29Å' scene=''> | + | <StructureSection load='4tr7' size='340' side='right'caption='[[4tr7]], [[Resolution|resolution]] 2.29Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4tr7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TR7 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4tr7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TR7 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tr7 OCA], [https://pdbe.org/4tr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tr7 RCSB], [https://www.ebi.ac.uk/pdbsum/4tr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tr7 ProSAT]</span></td></tr> |
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/DPO3B_MYCTO DPO3B_MYCTO] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 4tr7" style="background-color:#fffaf0;"></div> | ||
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+ | ==See Also== | ||
+ | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Burnouf | + | [[Category: Mycobacterium tuberculosis CDC1551]] |
- | [[Category: Ennifar | + | [[Category: Burnouf D]] |
- | [[Category: Olieric | + | [[Category: Ennifar E]] |
- | [[Category: Wolff | + | [[Category: Olieric V]] |
- | + | [[Category: Wolff P]] | |
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Current revision
Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis
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