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4rsy

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(New page: '''Unreleased structure''' The entry 4rsy is ON HOLD Authors: Ping, Ouyang, Weiqiang, Lu, Kunqiang, Cui, Jin, Huang Description: Crystal structures of the Human leukotriene A4 Hydrolas...)
Current revision (09:00, 20 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4rsy is ON HOLD
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==Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7==
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<StructureSection load='4rsy' size='340' side='right'caption='[[4rsy]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rsy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RSY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=B3N:4-(DIMETHYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]BENZAMIDE'>B3N</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsy OCA], [https://pdbe.org/4rsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rsy RCSB], [https://www.ebi.ac.uk/pdbsum/4rsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rsy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LKHA4_HUMAN LKHA4_HUMAN] Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:1975494</ref> <ref>PMID:2244921</ref> <ref>PMID:12207002</ref> <ref>PMID:11917124</ref> <ref>PMID:15078870</ref> <ref>PMID:18804029</ref>
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Authors: Ping, Ouyang, Weiqiang, Lu, Kunqiang, Cui, Jin, Huang
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==See Also==
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*[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]]
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Description: Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cui K]]
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[[Category: Huang J]]
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[[Category: Lu W]]
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[[Category: Ouyang P]]

Current revision

Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7

PDB ID 4rsy

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