4nnt
From Proteopedia
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==Crystal structure of FABP4 in complex with novel inhibitor== | ==Crystal structure of FABP4 in complex with novel inhibitor== | ||
| - | <StructureSection load='4nnt' size='340' side='right' caption='[[4nnt]], [[Resolution|resolution]] 1.53Å' scene=''> | + | <StructureSection load='4nnt' size='340' side='right'caption='[[4nnt]], [[Resolution|resolution]] 1.53Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nnt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNT OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4nnt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=76D:2,4,6-TRI(PROPAN-2-YL)BENZOIC+ACID'>76D</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnt OCA], [https://pdbe.org/4nnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnt RCSB], [https://www.ebi.ac.uk/pdbsum/4nnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnt ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chen TT]] |
| - | [[Category: | + | [[Category: Liu QF]] |
| - | [[Category: | + | [[Category: Xu YC]] |
Current revision
Crystal structure of FABP4 in complex with novel inhibitor
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Categories: Homo sapiens | Large Structures | Chen TT | Liu QF | Xu YC
