3eku
From Proteopedia
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==Crystal Structure of Monomeric Actin bound to Cytochalasin D== | ==Crystal Structure of Monomeric Actin bound to Cytochalasin D== | ||
- | <StructureSection load='3eku' size='340' side='right' caption='[[3eku]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3eku' size='340' side='right'caption='[[3eku]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3eku]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3eku]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EKU FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CY9:(3S,3AR,4S,6S,6AR,7E,10S,12R,13E,15R,15AR)-3-BENZYL-6,12-DIHYDROXY-4,10,12-TRIMETHYL-5-METHYLIDENE-1,11-DIOXO-2,3,3A,4,5,6,6A,9,10,11,12,15-DODECAHYDRO-1H-CYCLOUNDECA[D]ISOINDOL-15-YL+ACETATE'>CY9</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CY9:(3S,3AR,4S,6S,6AR,7E,10S,12R,13E,15R,15AR)-3-BENZYL-6,12-DIHYDROXY-4,10,12-TRIMETHYL-5-METHYLIDENE-1,11-DIOXO-2,3,3A,4,5,6,6A,9,10,11,12,15-DODECAHYDRO-1H-CYCLOUNDECA[D]ISOINDOL-15-YL+ACETATE'>CY9</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eku OCA], [https://pdbe.org/3eku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eku RCSB], [https://www.ebi.ac.uk/pdbsum/3eku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eku ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 3eku" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Actin|Actin]] | + | *[[Actin 3D structures|Actin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
- | [[Category: Joel | + | [[Category: Large Structures]] |
- | [[Category: Lowey | + | [[Category: Joel PB]] |
- | [[Category: Nair | + | [[Category: Lowey S]] |
- | [[Category: Rould | + | [[Category: Nair UB]] |
- | [[Category: Trybus | + | [[Category: Rould MA]] |
- | [[Category: Wan | + | [[Category: Trybus KM]] |
- | + | [[Category: Wan Q]] | |
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Current revision
Crystal Structure of Monomeric Actin bound to Cytochalasin D
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Categories: Drosophila melanogaster | Large Structures | Joel PB | Lowey S | Nair UB | Rould MA | Trybus KM | Wan Q