2xvm

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==CRYSTAL STRUCTURE OF THE TELLURITE DETOXIFICATION PROTEIN TEHB FROM E. COLI IN COMPLEX WITH SAH==
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<StructureSection load='2xvm' size='340' side='right' caption='[[2xvm]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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==Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with SAH==
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<StructureSection load='2xvm' size='340' side='right'caption='[[2xvm]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XVM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xvm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XVM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xva|2xva]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xvm RCSB], [http://www.ebi.ac.uk/pdbsum/2xvm PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvm OCA], [https://pdbe.org/2xvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xvm RCSB], [https://www.ebi.ac.uk/pdbsum/2xvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xvm ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TEHB_ECOLI TEHB_ECOLI] S-adenosyl-L-methionine dependent methyltransferase that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Can not methylate arsenic compounds.<ref>PMID:11053398</ref> <ref>PMID:21244361</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xvm" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Beis, K]]
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[[Category: Large Structures]]
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[[Category: Cameron, A D]]
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[[Category: Beis K]]
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[[Category: Choudhury, H G]]
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[[Category: Cameron AD]]
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[[Category: Iwata, S]]
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[[Category: Choudhury HG]]
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[[Category: Antibiotic resistance]]
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[[Category: Iwata S]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with SAH

PDB ID 2xvm

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