3eb0

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==Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804==
==Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804==
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<StructureSection load='3eb0' size='340' side='right' caption='[[3eb0]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='3eb0' size='340' side='right'caption='[[3eb0]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3eb0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EB0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3eb0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EB0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DRK:3-({[(3S)-3,4-DIHYDROXYBUTYL]OXY}AMINO)-1H,2H-2,3-BIINDOL-2-ONE'>DRK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DRK:3-({[(3S)-3,4-DIHYDROXYBUTYL]OXY}AMINO)-1H,2H-2,3-BIINDOL-2-ONE'>DRK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd4_240 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 Cryptosporidium parvum Iowa II])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb0 OCA], [https://pdbe.org/3eb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eb0 RCSB], [https://www.ebi.ac.uk/pdbsum/3eb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eb0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eb0 RCSB], [http://www.ebi.ac.uk/pdbsum/3eb0 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A3FQN0_CRYPI A3FQN0_CRYPI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eb0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cryptosporidium parvum iowa ii]]
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[[Category: Cryptosporidium parvum Iowa II]]
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[[Category: Ali, A]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Ali A]]
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[[Category: Bochkarev, A]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M]]
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[[Category: Bountra C]]
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[[Category: Fedorov, O]]
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[[Category: Edwards AM]]
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[[Category: Hui, R]]
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[[Category: Fedorov O]]
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[[Category: Kozieradzki, I]]
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[[Category: Hui R]]
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[[Category: Lam, A]]
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[[Category: Kozieradzki I]]
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[[Category: Lew, J]]
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[[Category: Lam A]]
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[[Category: Lin, Y H]]
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[[Category: Lew J]]
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[[Category: Structural genomic]]
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[[Category: Lin YH]]
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[[Category: Schapira, M]]
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[[Category: Schapira M]]
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[[Category: Vedadi, M]]
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[[Category: Vedadi M]]
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[[Category: Wasney, G]]
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[[Category: Wasney G]]
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[[Category: Wernimont, A K]]
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[[Category: Wernimont AK]]
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[[Category: Wilstrom, M]]
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[[Category: Wilstrom M]]
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[[Category: Zhao, Y]]
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[[Category: Zhao Y]]
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[[Category: Atp-binding]]
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[[Category: Kinase]]
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[[Category: Kinase cryptosporidium parvum]]
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[[Category: Nucleotide-binding]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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[[Category: Unknown function]]
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Current revision

Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804

PDB ID 3eb0

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