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4wxl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin== | |
| - | + | <StructureSection load='4wxl' size='340' side='right'caption='[[4wxl]], [[Resolution|resolution]] 2.33Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wxl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_86-028NP Haemophilus influenzae 86-028NP]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WXL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wxl OCA], [https://pdbe.org/4wxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wxl RCSB], [https://www.ebi.ac.uk/pdbsum/4wxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wxl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DEF_HAEI8 DEF_HAEI8] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Haemophilus influenzae 86-028NP]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Addlagatta A]] | ||
| + | [[Category: Kishor C]] | ||
Current revision
Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin
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