3ex8

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==Complex structure of bacillus subtilis RibG reduction mechanism in riboflavin biosynthesis==
==Complex structure of bacillus subtilis RibG reduction mechanism in riboflavin biosynthesis==
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<StructureSection load='3ex8' size='340' side='right' caption='[[3ex8]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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<StructureSection load='3ex8' size='340' side='right'caption='[[3ex8]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ex8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EX8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EX8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ex8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EX8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AIF:[(2R,3S,4R,5E)-5-[(5-AMINO-2,6-DIOXO-3H-PYRIMIDIN-4-YL)IMINO]-2,3,4-TRIHYDROXY-PENTYL]+DIHYDROGEN+PHOSPHATE'>AIF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b3z|2b3z]], [[2d5n|2d5n]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIF:[(2R,3S,4R,5E)-5-[(5-AMINO-2,6-DIOXO-3H-PYRIMIDIN-4-YL)IMINO]-2,3,4-TRIHYDROXY-PENTYL]+DIHYDROGEN+PHOSPHATE'>AIF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU23280, ribD, ribG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ex8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ex8 OCA], [https://pdbe.org/3ex8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ex8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ex8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ex8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ex8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ex8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ex8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ex8 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIBD_BACSU RIBD_BACSU] Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3ex8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3ex8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ex8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ex8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Chen, S C]]
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[[Category: Large Structures]]
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[[Category: Liaw, S H]]
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[[Category: Chen SC]]
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[[Category: Lin, Y H]]
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[[Category: Liaw SH]]
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[[Category: Yu, H C]]
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[[Category: Lin YH]]
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[[Category: Alpha/beta/alpha]]
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[[Category: Yu HC]]
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[[Category: Deaminase domain]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase domain]]
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[[Category: Riboflavin biosynthesis]]
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Current revision

Complex structure of bacillus subtilis RibG reduction mechanism in riboflavin biosynthesis

PDB ID 3ex8

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