3ks0

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==Crystal structure of the heme domain of flavocytochrome b2 in complex with Fab B2B4==
==Crystal structure of the heme domain of flavocytochrome b2 in complex with Fab B2B4==
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<StructureSection load='3ks0' size='340' side='right' caption='[[3ks0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='3ks0' size='340' side='right'caption='[[3ks0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ks0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KS0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ks0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KS0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fcb|1fcb]], [[1kbi|1kbi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYB2, YML054C, YM9958.08C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ks0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ks0 OCA], [https://pdbe.org/3ks0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ks0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ks0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ks0 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase_(cytochrome) L-lactate dehydrogenase (cytochrome)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.2.3 1.1.2.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ks0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ks0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ks0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ks0 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYB2_YEAST CYB2_YEAST]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/3ks0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/3ks0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ks0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ks0" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Flavocytochrome|Flavocytochrome]]
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Golinelli-Pimpaneau, B]]
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[[Category: Golinelli-Pimpaneau B]]
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[[Category: Le, K H.D]]
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[[Category: Le KHD]]
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[[Category: Lederer, F]]
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[[Category: Lederer F]]
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[[Category: Antibody]]
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[[Category: Domain mobility]]
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[[Category: Electron transfer]]
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[[Category: Electron transport]]
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[[Category: Epitope]]
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[[Category: Fab]]
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[[Category: Flavocytochrome b2]]
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[[Category: Flavoprotein]]
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[[Category: Fmn]]
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[[Category: Heme]]
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[[Category: Heme domain]]
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[[Category: Metal-binding]]
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[[Category: Mitochondrion]]
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[[Category: Oxidoreductase]]
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[[Category: Respiratory chain]]
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[[Category: Transit peptide]]
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[[Category: Transport]]
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Current revision

Crystal structure of the heme domain of flavocytochrome b2 in complex with Fab B2B4

PDB ID 3ks0

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