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3mmv

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==Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation==
==Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation==
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<StructureSection load='3mmv' size='340' side='right' caption='[[3mmv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3mmv' size='340' side='right'caption='[[3mmv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mmv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MMV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MMV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hf4|2hf4]], [[3mn5|3mn5]], [[3mn6|3mn6]], [[3mn7|3mn7]], [[3mn9|3mn9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mmv OCA], [https://pdbe.org/3mmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mmv RCSB], [https://www.ebi.ac.uk/pdbsum/3mmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mmv ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Act5C, CG4027 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster]), spir, p150-Spir, CG10076 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mmv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mmv RCSB], [http://www.ebi.ac.uk/pdbsum/3mmv PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3mmv" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Actin|Actin]]
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*[[Actin 3D structures|Actin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Ducka, A M]]
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[[Category: Large Structures]]
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[[Category: Holak, T A]]
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[[Category: Ducka AM]]
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[[Category: Huber, R]]
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[[Category: Holak TA]]
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[[Category: Popowicz, G M]]
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[[Category: Huber R]]
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[[Category: Sitar, T]]
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[[Category: Popowicz GM]]
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[[Category: Actin complex]]
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[[Category: Sitar T]]
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[[Category: Contractile protein-protein binding complex]]
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[[Category: Spire]]
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[[Category: Wh2 domain]]
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Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation

PDB ID 3mmv

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