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3nbl

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==Crystal Structure of BlaC-E166A covalently bound with Cefuroxime==
==Crystal Structure of BlaC-E166A covalently bound with Cefuroxime==
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<StructureSection load='3nbl' size='340' side='right' caption='[[3nbl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3nbl' size='340' side='right'caption='[[3nbl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nbl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NBL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nbl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NBL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXF:(2R)-5-[(CARBAMOYLOXY)METHYL]-2-[(1R)-1-{[(2Z)-2-(FURAN-2-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>DXF</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXF:(2R)-5-[(CARBAMOYLOXY)METHYL]-2-[(1R)-1-{[(2Z)-2-(FURAN-2-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>DXF</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nbl OCA], [https://pdbe.org/3nbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nbl RCSB], [https://www.ebi.ac.uk/pdbsum/3nbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nbl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nbl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nbl RCSB], [http://www.ebi.ac.uk/pdbsum/3nbl PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Blanchard, J S]]
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[[Category: Blanchard JS]]
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[[Category: Tremblay, L W]]
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[[Category: Tremblay LW]]
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[[Category: Beta-lactam covalent adduct]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Penicillin binding protein]]
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Current revision

Crystal Structure of BlaC-E166A covalently bound with Cefuroxime

PDB ID 3nbl

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