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3n9s

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==Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)- glycolohydroxamic acid bis-phosphate, a competitive inhibitor==
==Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)- glycolohydroxamic acid bis-phosphate, a competitive inhibitor==
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<StructureSection load='3n9s' size='340' side='right' caption='[[3n9s]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='3n9s' size='340' side='right'caption='[[3n9s]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3n9s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N9S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N9S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3n9s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_51 Helicobacter pylori 51]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N9S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TD4:4-{HYDROXY[(PHOSPHONOOXY)ACETYL]AMINO}BUTYL+DIHYDROGEN+PHOSPHATE'>TD4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c4u|3c4u]], [[3c52|3c52]], [[3c56|3c56]], [[3n9r|3n9r]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TD4:4-{HYDROXY[(PHOSPHONOOXY)ACETYL]AMINO}BUTYL+DIHYDROGEN+PHOSPHATE'>TD4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALF_HELPY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n9s OCA], [https://pdbe.org/3n9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n9s RCSB], [https://www.ebi.ac.uk/pdbsum/3n9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n9s ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n9s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n9s RCSB], [http://www.ebi.ac.uk/pdbsum/3n9s PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0IR47_HELP1 D0IR47_HELP1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3n9s" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Aldolase|Aldolase]]
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*[[Aldolase 3D structures|Aldolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fructose-bisphosphate aldolase]]
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[[Category: Helicobacter pylori 51]]
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[[Category: Helicobacter pylori]]
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[[Category: Large Structures]]
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[[Category: Coincon, M]]
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[[Category: Coincon M]]
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[[Category: Sygusch, S]]
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[[Category: Sygusch S]]
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[[Category: Class ii]]
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[[Category: Fbp aldolase]]
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[[Category: Inhibitor]]
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[[Category: Lyase]]
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[[Category: Lyase-lyase inhibitor complex]]
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Current revision

Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)- glycolohydroxamic acid bis-phosphate, a competitive inhibitor

PDB ID 3n9s

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