Ribosomal protein L16
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | + | <StructureSection load='1wki' size='350' side='right' scene='' caption='Ribosomal protein L16 (PDB code [[1wki]])'> | |
| + | == Function == | ||
| + | '''Ribosomal protein L16''' (RPL16) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It binds to 23S RRNA and is located at the A site of the peptidyltransferase center<ref>PMID:15561149</ref>. | ||
| - | + | == Relevance == | |
| - | + | Mutations in RPL16 confer reduced susceptibility to the antibiotic evernimicin<ref>PMID:10681347</ref>. | |
| + | </StructureSection> | ||
== 3D Structures of Ribosomal protein L16 == | == 3D Structures of Ribosomal protein L16 == | ||
| Line 12: | Line 15: | ||
**[[1wki]] – TtRPL16 – ''Thermus thermophilus'' - NMR<BR /> | **[[1wki]] – TtRPL16 – ''Thermus thermophilus'' - NMR<BR /> | ||
| + | **[[4cug]] – RPL16 + RPL16 arginyl hydroxylase – ''Rhodothermus marinus''<br /> | ||
*Ribosomal protein L16 in part of 50S subunit | *Ribosomal protein L16 in part of 50S subunit | ||
**[[1njm]], [[1njp]] – DrRPL16 + 23S RRNA + tRNA acceptor stEM mimic + general stress protein CTC + antibiotic - ''Deinococcus radiodurans''<br /> | **[[1njm]], [[1njp]] – DrRPL16 + 23S RRNA + tRNA acceptor stEM mimic + general stress protein CTC + antibiotic - ''Deinococcus radiodurans''<br /> | ||
| + | **[[1y69]] - DrRPL16 + RPL27 + 23S RRNA +5S RRNA + ribosome recycling factor + ribosome releasing factor<br /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
| |||||||||||
3D Structures of Ribosomal protein L16
Updated on 01-October-2017
References
- ↑ Nishimura M, Yoshida T, Shirouzu M, Terada T, Kuramitsu S, Yokoyama S, Ohkubo T, Kobayashi Y. Solution structure of ribosomal protein L16 from Thermus thermophilus HB8. J Mol Biol. 2004 Dec 10;344(5):1369-83. PMID:15561149 doi:10.1016/j.jmb.2004.10.011
- ↑ Adrian PV, Zhao W, Black TA, Shaw KJ, Hare RS, Klugman KP. Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action. Antimicrob Agents Chemother. 2000 Mar;44(3):732-8. PMID:10681347
