3nkh

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==Crystal Structure of Integrase from MRSA strain Staphylococcus aureus==
==Crystal Structure of Integrase from MRSA strain Staphylococcus aureus==
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<StructureSection load='3nkh' size='340' side='right' caption='[[3nkh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='3nkh' size='340' side='right'caption='[[3nkh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nkh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_usa300_tch1516 Staphylococcus aureus subsp. aureus usa300_tch1516]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NKH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nkh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_USA300_TCH1516 Staphylococcus aureus subsp. aureus USA300_TCH1516]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NKH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">USA300HOU_0850 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=451516 Staphylococcus aureus subsp. aureus USA300_TCH1516])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nkh OCA], [https://pdbe.org/3nkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nkh RCSB], [https://www.ebi.ac.uk/pdbsum/3nkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nkh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nkh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nkh RCSB], [http://www.ebi.ac.uk/pdbsum/3nkh PDBsum]</span></td></tr>
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</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nkh_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nkh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nkh ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Retroviral Integrase|Retroviral Integrase]]
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*[[Integrase|Integrase]]
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*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Staphylococcus aureus subsp. aureus usa300_tch1516]]
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[[Category: Large Structures]]
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[[Category: Gornicki, P]]
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[[Category: Staphylococcus aureus subsp. aureus USA300_TCH1516]]
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[[Category: Joachimiak, A]]
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[[Category: Gornicki P]]
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[[Category: Kim, Y]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Kim Y]]
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[[Category: Tesar, C]]
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[[Category: Tesar C]]
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[[Category: Alpha-fold]]
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[[Category: Mcsg]]
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[[Category: Mrsa protein]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Recombination]]
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Current revision

Crystal Structure of Integrase from MRSA strain Staphylococcus aureus

PDB ID 3nkh

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