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3q7h
From Proteopedia
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==Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii== | ==Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii== | ||
| - | <StructureSection load='3q7h' size='340' side='right' caption='[[3q7h]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3q7h' size='340' side='right'caption='[[3q7h]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q7h]] is a 14 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q7h]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxbr Coxbr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7H FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">clpP, COXBURSA331_A1213 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">clpP, COXBURSA331_A1213 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=360115 COXBR])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7h OCA], [https://pdbe.org/3q7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7h RCSB], [https://www.ebi.ac.uk/pdbsum/3q7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7h ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/CLPP_COXBR CLPP_COXBR]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | ||
==See Also== | ==See Also== | ||
| - | *[[Clp | + | *[[Clp protease 3D structures|Clp protease 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Coxbr]] |
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Anderson, S M]] | [[Category: Anderson, S M]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
Current revision
Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii
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