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4dza

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==Crystal structure of a lysine racemase within internal aldimine linkage==
==Crystal structure of a lysine racemase within internal aldimine linkage==
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<StructureSection load='4dza' size='340' side='right' caption='[[4dza]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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<StructureSection load='4dza' size='340' side='right'caption='[[4dza]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4dza]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DZA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4dza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DZA FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysine_racemase Lysine racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.5 5.1.1.5] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dza OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dza RCSB], [http://www.ebi.ac.uk/pdbsum/4dza PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dza OCA], [https://pdbe.org/4dza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dza RCSB], [https://www.ebi.ac.uk/pdbsum/4dza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dza ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYR_PROMI LYR_PROMI] Amino-acid racemase that catalyzes the interconversion of L-lysine and D-lysine. To a lesser extent, is also able to interconvert arginine enantiomers (Ref.1, PubMed:23118975). Cannot use methionine, asparagine, alanine, leucine, glutamine, phenylalanine and histidine as substrates (Ref.1).<ref>PMID:23118975</ref> [UniProtKB:I0J1I6]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4dza" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lysine racemase]]
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[[Category: Large Structures]]
[[Category: Proteus mirabilis]]
[[Category: Proteus mirabilis]]
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[[Category: Wang, W C]]
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[[Category: Wang WC]]
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[[Category: Wu, H M]]
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[[Category: Wu HM]]
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[[Category: Isomerase]]
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[[Category: Plp binding]]
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[[Category: Racemization]]
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Current revision

Crystal structure of a lysine racemase within internal aldimine linkage

PDB ID 4dza

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