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4esq

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==Crystal structure of the extracellular domain of PknH from Mycobacterium tuberculosis==
==Crystal structure of the extracellular domain of PknH from Mycobacterium tuberculosis==
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<StructureSection load='4esq' size='340' side='right' caption='[[4esq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4esq' size='340' side='right'caption='[[4esq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4esq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ESQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4esq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=TB:TERBIUM(III)+ION'>TB</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=TB:TERBIUM(III)+ION'>TB</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pknH, Rv1266c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esq OCA], [https://pdbe.org/4esq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esq RCSB], [https://www.ebi.ac.uk/pdbsum/4esq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4esq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4esq RCSB], [http://www.ebi.ac.uk/pdbsum/4esq PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PKNH_MYCTU PKNH_MYCTU] May regulate bacterial growth in response to external signals to facilitate adaptation to the host environment. In vitro, phosphorylates several substrates such as EmbR, DevR (DosR), DacB1 and Rv0681.<ref>PMID:14690440</ref> <ref>PMID:15043876</ref> <ref>PMID:16077122</ref> <ref>PMID:16585755</ref> <ref>PMID:16817899</ref> <ref>PMID:17286964</ref> <ref>PMID:20630871</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4esq" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Large Structures]]
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[[Category: Alber, T]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Cavazos, A]]
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[[Category: Alber T]]
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[[Category: Prigozhin, D M]]
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[[Category: Cavazos A]]
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[[Category: Membrane]]
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[[Category: Prigozhin DM]]
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[[Category: Receptor kinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the extracellular domain of PknH from Mycobacterium tuberculosis

PDB ID 4esq

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