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3vrn

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==Crystal structure of the tyrosine kinase binding domain of Cbl-c==
==Crystal structure of the tyrosine kinase binding domain of Cbl-c==
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<StructureSection load='3vrn' size='340' side='right' caption='[[3vrn]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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<StructureSection load='3vrn' size='340' side='right'caption='[[3vrn]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vrn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VRN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vrn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VRN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vro|3vro]], [[3vrp|3vrp]], [[3vrq|3vrq]], [[3vrr|3vrr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBLC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vrn OCA], [https://pdbe.org/3vrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vrn RCSB], [https://www.ebi.ac.uk/pdbsum/3vrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vrn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vrn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vrn RCSB], [http://www.ebi.ac.uk/pdbsum/3vrn PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CBLC_HUMAN CBLC_HUMAN] Regulator of EGFR mediated signal transduction.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3vrn" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Isozaki, Y]]
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[[Category: Large Structures]]
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[[Category: Nakagawa, A]]
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[[Category: Isozaki Y]]
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[[Category: Suzuki, M]]
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[[Category: Nakagawa A]]
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[[Category: Takeshita, K]]
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[[Category: Suzuki M]]
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[[Category: Tezuka, T]]
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[[Category: Takeshita K]]
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[[Category: Yamamoto, T]]
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[[Category: Tezuka T]]
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[[Category: Yamanashi, Y]]
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[[Category: Yamamoto T]]
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[[Category: Yamashita, E]]
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[[Category: Yamanashi Y]]
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[[Category: Calcium-binding ef hand]]
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[[Category: Yamashita E]]
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[[Category: Divergent sh2 domain]]
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[[Category: Protein binding]]
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[[Category: Ptb domain]]
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[[Category: Regulator of egfr mediated signal transduction]]
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[[Category: Ubiquitously expressed]]
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Current revision

Crystal structure of the tyrosine kinase binding domain of Cbl-c

PDB ID 3vrn

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