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4h75

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==Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide==
==Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide==
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<StructureSection load='4h75' size='340' side='right' caption='[[4h75]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4h75' size='340' side='right'caption='[[4h75]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4h75]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H75 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H75 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4h75]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H75 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.098&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPIN1, OCR, SPIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h75 OCA], [https://pdbe.org/4h75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h75 RCSB], [https://www.ebi.ac.uk/pdbsum/4h75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h75 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h75 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h75 RCSB], [http://www.ebi.ac.uk/pdbsum/4h75 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4h75" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Spindlin|Spindlin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Rao, Z]]
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[[Category: Large Structures]]
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[[Category: Wang, M]]
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[[Category: Rao Z]]
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[[Category: Wang, W]]
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[[Category: Wang M]]
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[[Category: Wang, Y]]
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[[Category: Wang W]]
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[[Category: Xu, R M]]
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[[Category: Wang Y]]
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[[Category: Yang, N]]
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[[Category: Xu RM]]
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[[Category: Zhao, Q]]
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[[Category: Yang N]]
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[[Category: Zhu, B]]
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[[Category: Zhao Q]]
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[[Category: Gene regulation]]
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[[Category: Zhu B]]
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[[Category: H3k4me3 binding]]
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[[Category: Methylation]]
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[[Category: Tudor domain]]
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Current revision

Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide

PDB ID 4h75

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