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4h6d
From Proteopedia
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==Crystal structure of PLP-soaked HMP synthase Thi5 from S. cerevisiae== | ==Crystal structure of PLP-soaked HMP synthase Thi5 from S. cerevisiae== | ||
| - | <StructureSection load='4h6d' size='340' side='right' caption='[[4h6d]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='4h6d' size='340' side='right'caption='[[4h6d]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4h6d]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4h6d]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H6D FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h6d OCA], [https://pdbe.org/4h6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h6d RCSB], [https://www.ebi.ac.uk/pdbsum/4h6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h6d ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THI5_YEAST THI5_YEAST] Proposed biosynthetic enzyme involved in pyrimidine biosynthesis pathway above the hydroxymethyl-pyrimidine precursor leading to the thiamine moiety.<ref>PMID:12777485</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4h6d" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Coquille | + | [[Category: Coquille SC]] |
| - | [[Category: Fitzpatrick | + | [[Category: Fitzpatrick T]] |
| - | [[Category: Roux | + | [[Category: Roux C]] |
| - | [[Category: Thore | + | [[Category: Thore S]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of PLP-soaked HMP synthase Thi5 from S. cerevisiae
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