4rwh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4rwh is ON HOLD Authors: Fedorov, A.A., Fedorov, E.V., Samanta, D., Hillerich, B., Seidel, R.D., Almo, S.C. Description: Crystal structure of T cel...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of T cell costimulatory ligand B7-1 (CD80)== | |
| - | + | <StructureSection load='4rwh' size='340' side='right'caption='[[4rwh]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RWH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.802Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rwh OCA], [https://pdbe.org/4rwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rwh RCSB], [https://www.ebi.ac.uk/pdbsum/4rwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rwh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD80_MOUSE CD80_MOUSE] Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Almo SC]] | ||
| + | [[Category: Fedorov AA]] | ||
| + | [[Category: Fedorov EV]] | ||
| + | [[Category: Hillerich B]] | ||
| + | [[Category: Samanta D]] | ||
| + | [[Category: Seidel RD]] | ||
Current revision
Crystal structure of T cell costimulatory ligand B7-1 (CD80)
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