4x46
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4x46 is ON HOLD Authors: Balaev, V.V., Lashkov, A.A., Prokofev, I.I., Gabdoulkhakov, A.G., Betzel, C., Mikhailov, A.M. Description: X-RAY structure...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A== | |
| - | + | <StructureSection load='4x46' size='340' side='right'caption='[[4x46]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x46]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X46 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [https://pdbe.org/4x46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [https://www.ebi.ac.uk/pdbsum/4x46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x46 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] | ||
| + | [[Category: Balaev VV]] | ||
| + | [[Category: Betzel C]] | ||
| + | [[Category: Gabdoulkhakov AG]] | ||
| + | [[Category: Lashkov AA]] | ||
| + | [[Category: Mikhailov AM]] | ||
| + | [[Category: Prokofev II]] | ||
Current revision
X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A
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