4il2
From Proteopedia
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==Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)== | ==Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)== | ||
| - | <StructureSection load='4il2' size='340' side='right' caption='[[4il2]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='4il2' size='340' side='right'caption='[[4il2]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4il2]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4il2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IL2 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4il2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4il2 OCA], [https://pdbe.org/4il2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4il2 RCSB], [https://www.ebi.ac.uk/pdbsum/4il2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4il2 ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MAND_ECOL6 MAND_ECOL6] Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Escherichia coli | + | [[Category: Escherichia coli CFT073]] |
| - | [[Category: Gerlt | + | [[Category: Large Structures]] |
| - | [[Category: Imker | + | [[Category: Gerlt JA]] |
| - | [[Category: Lukk | + | [[Category: Imker HJ]] |
| - | [[Category: Nair | + | [[Category: Lukk T]] |
| - | [[Category: Wichelecki | + | [[Category: Nair SK]] |
| - | + | [[Category: Wichelecki D]] | |
| - | + | ||
Current revision
Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585)
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